Pfizer

Senior Director, Global Obesity Commercial

In short

Senior strategic leadership role at Pfizer shaping global commercial development strategy for the obesity franchise, driving portfolio-level strategy across multiple pipeline assets and indications and leading launch readiness integration with R&D, Commercial, Finance, BD, and regional stakeholders. Requires 12+ years in commercial/R&D strategy, portfolio strategy, or consulting, strong scientific and financial acumen, and executive presence; obesity or cardiometabolic experience strongly preferred. Based in New York City, with a base salary of $214,900–$358,100 plus bonus and long-term incentives; no visa sponsorship is offered.

ROLE SUMMARY
The Senior Director, Global Obesity Commercial Development serves as a senior strategic leader responsible for shaping Pfizer's portfolio-level commercial development strategy for the global obesity franchise. This role leads cross-functional strategic integration, drives end-to-end commercial strategy across multiple pipeline assets and indications, and partners with senior leadership on high-impact decisions.
Operating as a senior strategic leader, this role requires a high sense of urgency, the ability to navigate significant ambiguity, and the capability to fluidly shift between asset-level detail and portfolio-wide strategic direction. The Senior Director must demonstrate exceptional cross-functional leadership and communication skills, orchestrating complex integrations across clinical, commercial, and operational stakeholders. As the obesity portfolio progresses toward late-stage development and early commercialization, this position is critical in ensuring portfolio-level strategic coherence, enterprise-aligned decision-making, and executional readiness across the franchise. A successful candidate will bring deep scientific and business acumen, strong strategic judgment, and a demonstrated ability to influence senior leaders and governance bodies.
ROLE RESPONSIBILITIES
Portfolio-Level Commercial Strategy Leadership
•Lead the shaping of Pfizer's overarching commercial vision and long-range portfolio strategy.
•Translate market and clinical signals into portfolio-level implications and strategic choices.
•Partner with R&D, Commercial, Finance, and BD to influence investment and lifecycle strategies.
•Oversee forecasting frameworks and scenario planning.
•Identify and shape BD opportunities.
Launch Readiness & Cross-Functional Integration
•Lead global launch readiness strategy across multiple assets and indications.
•Serve as senior integrator across Commercial, R&D, GAV, PGS, BD, and regions.
•Shape capabilities and operating model required to deliver strategy.
•Ensure alignment across global, regional, and market stakeholders.
QUALIFICATIONS
•Bachelor's degree required; advanced degree strongly preferred.
Experience
•12+ years in commercial and R&D strategy, commercial development, portfolio strategy, or consulting.
•Strong scientific background.
•Leadership shaping end-to-end strategy across multiple assets.
•Strong financial acumen and experience influencing senior leadership.
•Exceptional communication and executive presence.
•Obesity or cardiometabolic experience strongly preferred.
Last day to apply: 11/12/2026
Compensation & Benefits
The annual base salary for this position ranges from $214,900.00 to $358,100.00. This position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in the share-based long-term incentive program. Benefits include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits including medical, prescription drug, dental and vision coverage. Pfizer compensation structures and benefit packages are aligned based on the location of hire; the United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. This position requires permanent work authorization in the United States.

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