Principal Scientist, Discovery Process Chemistry (DPC)

Our Company is currently seeking an exceptional scientific leader for our Discovery Process Chemistry (DPC) group at our Boston, MA site.

The core responsibility of the successful candidate will be to lead a team of scientists in the development of innovative solutions to complex chemistry problems across a diverse portfolio of projects and modalities in the discovery phase, from lead identification through candidate selection, with the goal to apply these solutions to facilitate medicinal chemistry research by overcoming synthetic bottlenecks, streamlining SAR analogue synthesis, and providing access to novel chemical space.

The position is also responsible for defining scalable synthetic routes and successfully transitioning candidate compounds from discovery into early development, as well as managing supply of Active Pharmaceutical Ingredients (APIs) at varying scales during this period. Close collaboration with chemistry colleagues in Medicinal Chemistry and Process Chemistry, as well as a broad array of other discovery and preclinical research groups, will be expected. As such, subject matter expertise in Medicinal or Process Chemistry is critical.

The candidate must be highly self-motivated, demonstrate strong leadership, possess strong experimental skills, have excellent written and oral communication abilities, collaborate effectively on multidisciplinary teams, and be able to demonstrate flexibility in adapting to change in a fast-paced, dynamic research environment. In addition to supervising direct scientific reports, the candidate is also expected to provide broader mentorship and expertise across the DPC group. The candidate will be expected to remain current with the latest synthetic methodologies, drive innovation, actively apply new concepts to continuously improve PR&D capabilities and expertise, and be active in the external scientific community via publications and external presentations.

Bioconjugation, Clinical Chemistry, Computational Chemistry, High-Throughput Experimentation (HTE), Inorganic Synthesis, Medicinal Chemistry, Organic Chemistry, Organic Synthesis, Organometallic Chemistry, Preclinical Research, Process Chemistry, Scientific Publishing, Structure Based Drug Design, Synthetic Chemistry

Preferred Skills: None specified

Primary location: USA - Massachusetts - Boston (MA Parcel B Laboratory)

The salary range for the primary location of this role is $176,200.00 - $277,300.00. This range reflects the Company's reasonable expectation of the base salary applicable to this role at the time of posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.