Johnson & Johnson

Senior Data Scientist - R&D DDSAI - Preclinical Sciences & Translational Safety

In short

This Senior Data Scientist role at Johnson & Johnson's R&D Data Science organization applies machine learning and data engineering to the Pharmaceutical Sciences & Translational Safety (PSTS) domain, building predictive models and AI-ready datasets from toxicology, PK/PD, and in vivo study data. It requires close collaboration with toxicologists, PK/PD specialists, and safety professionals to translate scientific study designs into computational models and pipelines. Candidates need an advanced degree (MS/PhD) in a relevant scientific or computational field, 2+ years applying ML/data engineering to biomedical datasets, and proficiency in Python/R, SQL, and cloud data tooling. The position can be based in Spring House, Pennsylvania, US, or in Belgium or Spain.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.
Job Function: Data Analytics & Computational Sciences
Job Sub Function: Data Science
Job Category: Scientific/Technology
All Job Posting Locations: Beerse, Antwerp, Belgium; Cornellà de Llobregat, Barcelona, Spain; Madrid, Spain; Spring House, Pennsylvania, United States of America
Job Description
The R&D Data Science organization is seeking a Senior Data Scientist to leverage advanced machine learning, robust data engineering techniques, and domain expertise to drive impactful decisions and generate actionable insights within the Pharmaceutical Sciences & Translational Safety (PSTS) organization. In this role, you will work closely with multidisciplinary teams—including toxicologists, PK/PD specialists, in vivo researchers, and safety professionals—to create AI-ready datasets, develop predictive models, and deliver analytical solutions that promote improved safety evaluations and facilitate translational research.
The successful candidate possesses hands-on experience in machine learning and data engineering, complemented by a solid understanding of toxicology, pharmacokinetics/pharmacodynamics (PK/PD), in vivo experimentation, and translational science. Additionally, this role requires strong communication and problem-solving skills, a passion for innovation, and the ability to adapt to evolving scientific challenges in pharmaceutical R&D.
Key Responsibilities
Machine Learning & Modeling
•Develop and deploy ML/AI models to support safety signal detection, dose selection, PK/PD modeling, toxicology insights, and translational interpretation.
•Implement representation‑learning, predictive modeling, and multivariate analytics for datasets spanning in vivo studies, in vitro assays, exposure‑response data, and pathology information.
•Partner with scientific SMEs to design modeling strategies aligned with PSTS decision points.
•Apply model governance, versioning, and validation standards consistent with R&D AI practices.
Data Engineering & Pipeline Development
•Build and maintain scalable data pipelines that integrate PSTS‑relevant data sources (e.g., toxicology studies, PK/PD datasets, biomarker readouts, animal study repositories).
•Transform raw experimental outputs into standardized, analysis‑ready, AI‑ready datasets using Python, R, and cloud‑native services.
•Contribute to harmonized scientific data models in collaboration with data engineering and ontology teams.
Scientific Domain Integration
•Work directly with toxicology, DMPK, and safety stakeholders to interpret scientific context and translate study designs into computational requirements.
•Apply understanding of mechanism‑based toxicology, exposure‑response concepts, and in vivo study structures to guide data transformations and modeling strategies.
•Enhance cross‑study comparability via standardized terminologies, metadata practices, and quality checks.
•Collaborate with PSTS functional experts, R&D Data Science teams, and platform architects to ensure high-quality, scalable data solutions.
Qualifications
Required
•Advanced degree (MS or PhD) in Data Science, Computational Biology, Toxicology, Pharmacology, Biomedical Engineering, Computer Science, or related field.
•2+ years of experience applying machine learning and/or data engineering to scientific or biomedical datasets.
•Proficiency with Python and/or R, SQL, and modern data engineering tooling (cloud computing, workflow orchestration, version control).
•Experience with ML model development, evaluation, and deployment pipelines.
•Experience working with biological, toxicology, PK/PD, or in vivo datasets.
Preferred
•Experience in safety sciences, ADME/DMPK, toxicogenomics, or biomarker analytics.
•Familiarity with scientific data formats (e.g., assay outputs, histopathology data, PK time-course datasets).
•Exposure to ontologies, semantic technologies, or knowledge graph integration for scientific domains.
•Experience with cloud‑based data architectures (AWS S3, Snowflake, Redshift).
•Understanding of regulatory data standards (e.g., SEND, CDISC).
Why This Role Is Unique
This is a rare opportunity to grow in one of the world's most ambitious and fastest-growing R&D Data Science organizations, shaping how PSTS data powers next‑generation therapies in the largest biomedical company on the planet. Your work will directly accelerate Johnson & Johnson's scientific discovery, fuel AI innovation, and impact patients globally.
Preferred Skills: Advanced Analytics, Business Intelligence (BI), Coaching, Collaboration, Critical Thinking, Data Analysis, Database Management, Data Privacy Standards, Data Reporting, Data Savvy, Data Science, Data Visualization, Econometric Models, Process Improvements, Technical Credibility, Technologically Savvy, Workflow Analysis
Benefits
Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company's long-term incentive program.
Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:
•Vacation – 120 hours per calendar year
•Sick time – 40 hours per calendar year; for employees who reside in the State of Colorado – 48 hours per calendar year; for employees who reside in the State of Washington – 56 hours per calendar year
•Holiday pay, including Floating Holidays – 13 days per calendar year
•Work, Personal and Family Time – up to 40 hours per calendar year
•Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
•Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
•Caregiver Leave – 80 hours in a 52-week rolling period
•Volunteer Leave – 32 hours per calendar year
•Military Spouse Time-Off – 80 hours per calendar year

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